Somewhere around 2003 – 2004, I purchased Frontline Plus from my Vet after a rescue we took in spread fleas to my other dogs. Literally, the instant I applied it to my youngest Beagle, she actually screamed – and her underside had turned bright red, like it had given her a first degree burn. Not only that, but it did nothing to rid the other dogs of fleas. We went to Bio Spot after that and have never had an adverse reaction, even when I was forced to use it on a dog with cancer being inundated with fleas and a few dogs who either had epilepsy or were prone to seizures.
