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  • in reply to: Galliprant for Osteoarthritis anyone? #105007 Report Abuse
    george h
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    I joined to share our experiences and suggest additional OA options because we found a vet that stays on the cutting edge of treatments.

    Our 14 yr old golden retriever had mild hip dysplasia when we rescued her, so our vet recommended feeding an rx diet with high fish oil and glucosamine content. After more than a decade, our golden has only mild arthritis in her lower spine and mild stiffness/weakness in her rear legs. Now Doggo’s ancient for the breed, perhaps it’s an outlier in general.

    Nevertheless, when the rx food manufacturer switched to rancid fish oils, Doggo (and the others) refused to eat the rx food. While researching new dog foods, we started feeding Doggo human grade (aka “my”) fish oil and glucosamine/msm supplements daily with a primary protein grain free diet. After four months, Doggo’s mobility/cognition was better than when eating the rx food. (Btw- Rancid fish oils actually cause inflammation in the body instead of reducing inflammation.)

    And because Doggo was moving better, Doggo was playing to the point of excess. The vet recommended a short course of rimadyl, but Doggo experienced a personality change on rimadyl. The obedient without fail Doggo refused to stay in the yard or come when called. It was terrifying.

    Our vet found the rimadyl side effect unusual, ran bloodwork (normal liver with slightly elevated kidneys) and offered newly available pentosan injections that lubricate the joints to relieve OA pain– without affecting kidney or liver function. We were told it may not alleviate all the pain, but Pentosan has worked wonders! We learned how to inject it (subcutaneously) so Doggo doesn’t have to endure a long ride for a maintenance dose, and at $20-$30 per dose, it was worth trying.

    But Doggo played to excess again and instead of rimadyl, the vet prescribed galliprant. At first galliprant didn’t seem to be as effective as rimadyl but it didn’t cause the personality changes rimadyl did. After a few days on galliprant though, Doggo was feeling better. The dose is just enough to provide relief without allowing Doggo to play as hard as a puppy.

    Again, Doggo may be the exception not having any GI issues with either rimadyl or galliprant– btw, wrapped in American cheese slices and given before the morning meal. Glucosamine and fish oil supplements (and/or pentosan injections) may have negligible effects in other dogs. The other supplements may or may not be helping: recently, we started giving Doggo vitamin C and cholodin supplements, in addition to a human Nicotinamide Riboside with Pterostilbene supplement. Perhaps even minimal dietary supplements/changes are cumulative– our current theory. Whatever the case, we hope someone else can benefit from knowing what we’ve found effective with Doggo.

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