[losul]

Hi weezer. Milk thistle had nothing to do at all, nada, with making my dog more susceptible to heartworms. I feel that other completely unrelated things I did/neglected to do, were to likely to blame.

I myself take milk thistle sometimes, I always have some on hand, but I’ve actually rarely given it to my dog, and not with any consistency, but that’s mainly because I forget, otherwise I wouldn’t have been afraid to give him a low dose regimen after oral ivermectin, as long as there is a reasonable time lapse after administration, but never concurrently with, immediately after, or in high doses.

I think you misunderstood. There’s only a very few drugs, where milk thistle is thought to decrease the efficacy, most of the drug interactions and most of the concerns are that milk thistle actually increase the efficacy of ( has the effect of increasing dosage) and slowing elimination times. It becomes even more of a concern with dogs might be dose sensitive, as those with the MDR-1 genetic defect.

Weezer BTW, I know I probably seem over reactive and emotional some times, LOL. But I assure you that I am all male. 🙂

• This reply was modified 10 years, 10 months ago by losul.