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Reply To: Pharmaceuticals and heartworm meds
Wow! Here are my thoughts regarding Peter Dobias’s recommendations…
Heartworm DNA testing. Dobias wrote “This test has virtually no false negatives, which is great news for your dog.”
PCR tests in general are very sensitive and so that statement may be technically true. But the manner in which he is applying the test I think false negatives will be the norm. The test is based on DNA which is in a cell’s nucleus. Heartworm larva migrate in the sub Q tissue. How is it that larva cells can get from the sub Q into the circulatory system? They are too big to cross vessel walls. The larva do leave the sub Q and enter the circulatory system and at that point I’d expect they can be detected. However the dog is now infected with young adult heartworms. The time frame to prevent infection has passed.
Preventatives are effective against young larva, the older the migrating larva are the less effective the kill rate. Even if this test can pickup migrating larva, by only testing every 4months, the infection cold be four months old and difficult to arrest at that point.
His temp data doesn’t look accurate. Heartworm development in the mosquito progresses with warmer temps. Units referred to as heartworm development units. need to accumulate. Sustained high temps are not required.
The reason for extending prevention beyond exposure dates is that it is documented that one dose of preventatives doesn’t always prevent infection. In one study one does didn’t prevent infection and three doses a month apart from each other did.
In my opinion the alternative program as outlined by Peter Dobias is reckless at best.
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Search Forums
Recent Topics
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Aion 2 Gear Upgrade Tips Every New Player Should Know
by
wild petals
3 days, 20 hours ago -
PVPBank: All Cryoshock Serpent Locations in Fisch Roblox Guide
by
Macro M
4 days, 23 hours ago -
SSEGold Arc Raiders Flickering Flames Event Guide Rewards Merit Candleberries
by
Macro M
5 days, 20 hours ago -
Best enrichment toys for a smart dog? Others are getting boring.
by
George Lawson
1 week, 2 days ago -
How Do You Handle Cost Challenges in Tunnel Construction Projects?
by
Flex Kingston
4 days, 23 hours ago
Recent Replies
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Ron Hunter on Fiber Supplement
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ahnahaa alenaha on How Do You Handle Cost Challenges in Tunnel Construction Projects?
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Carter Fisher on "American Journey" Dog Food who manufacturer's it?
-
shanaa ahnhaa on rsgoldfast OSRS is a vast and ever-evolving game experience
-
voldemar leo on How Do You Handle Cost Challenges in Tunnel Construction Projects?
-
Lis Tewert on Meijer Brand Dog Food
-
Otilia Becker on Precision Heat Treating – Annealing, Quenching, Tempering & Normalizing
-
Emilia Foster on dog vitamins
-
Israel Jennings on Supermarcat
-
Keti Elitzi on Chewy ingredient listing
-
Robert Butler on Score Big with Retro Bowl: A Nostalgic Touchdown Experience
-
voldemar leo on What health issues are you trying to address with this supplement?
-
Jeffrey Clarke on Choosing the Right Dog Food: Lessons from Strategy and Games
-
Robert Butler on The Right Stuff
-
Jeffrey Clarke on Whole Paws Review