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Reply To: Large and Giant Breed Puppy Nutrition

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losul
Member

Kms.
I’m really sorry I can’t answer many of your questions and I’m not qualified to give medical advice. I don’t know specifically what your vet prescribed the SMZ TMP for, if it was even for anything specific. It may not be effective against clostridium? I would ask questions of your vet, before carrying on.

c. difficile and c. perfingens are often culprits in humans. I think c. perfingens more often in dogs.

SMZ TMP (usage in humans) http://www.webmd.com/drugs/drug-64007-SMZ-TMP+DS+Oral.aspx?drugid=64007&drugname=SMZ-TMP+DS+Oral

“This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a resistant bacteria. This condition may occur while receiving treatment or even weeks to months after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell your doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool.”

“Use of this medication for prolonged or repeated periods may result in oral thrush or a new yeast infection (oral or vaginal fungal infection). Contact your doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms.”

About the kaolin (pro-pectin)

Kaolin Interactions

Kaolin pectin may decrease the absorption of drugs that chelate with aluminum salts (eg, digoxin, clindamycin, lincomycin). Until more information is available, avoid taking kaolin with drugs that chelate with aluminum. It may also decrease the absorption of trimethoprim and quinidine.

http://www.drugs.com/npp/kaolin.html

It looks like as long as you separate the doses enough, it may be O.K.

Trimethoprim (Proloprim) interacts with KAOLIN
Kaolin might decrease the absorption and decrease the effectiveness of trimethoprim (Proloprim), an antibiotic. To avoid a potential interaction, separate trimethoprim (Proloprim) and kaolin doses by at least two hours.

http://www.webmd.com/vitamins-supplements/ingredientmono-44-KAOLIN.aspx?activeIngredientId=44&activeIngredientName=KAOLIN

The questions about the probiotics and enzymes- I don’t know, but me, I would be leery of using the enzymes at least for the time being.

By lightly cooked meat, I meant cooked only enough to kill pathogens that may be present. The rice cooked per package directions should be fine.