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Reply To: Heartworms, need advice.

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losul
Member

Dori, I found this with some googling. I don’t think ivermectin shows on the list but that list isn’t all inclusive. I’ m sure you can find that ivermectin is metabolized by the same CYP3A4 enzyme in the liver, probaly other drugs in it’s class also. I pulled that up somewhere before, probably from the manufacturer’s site. I’ll look some more whenever i can get a chance. Most of the drug interactions it increases the efficacy, while there are a few it decreases it.

http://www.hcvadvocate.org/hepatitis/hepC/mthistle.html