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Joseph N
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May 27, 2017 at 10:49 pm in reply to: Low-fat healthy diet needed #101578 Report Abuse Edit Post Visibility
Joseph N
MemberHey All, my dog (2 yr old 40-45lb Plott Hound) probably has Chylothorax. It looks exactly like it but weāre waiting on test results to rule out lymphoma and infection.
Researching this online Iāve found (like you all) that I should add Rutin to her new low-fat diet. So I ordered some. Iām trying to understand the dosing though. From what I can tell Rutinās possible mechanisms for helping are poorly understood at best, but also that it has a very low or unknown toxicity. Iāve run across people citing 50 ā 100 mg/kg body weight as a recommended dose, but Iāve found no reason for those numbers. Is it pure guess work?
Iāve found the LD95 of Rutin for rats of 19.5 g/kg, which is enormous. Various sources claim no effects for male rats at all until somewhere between 500 ā 2500 mg/kg, and females can take even more. I havenāt found this data for dogs.
So, Iām betting dogs can take a lot more than 100 mg/kg, and I donāt know why thatās the number thatās floating around everywhere. My guess is some researcher picked it out of the air and ran with it. It seemed safe, so it stuck. For sure though, there seems to be a big lack of info on Rutin as a treatment :/
I think Iām going to give my dog more, but Iām trying to decide how much. For now Iāll start off at ~ 200mg/kg. Perhaps sheāll just pee it out like taking a lot of Vitamin C, but it seems very unlikely to hurt.
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