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Reply To: So it is kidney failure…
Epikitin is used primarily as a phosphate binder in chronic kidney disease. From what I’ve read, the main ingredient, chitosan, is the phosphate binder but is also a mild prebiotic (shown to work better than FOS but I haven’t seen studies as compared to acacia fiber).
I have some concerns about epikitin – it has hydrolyzed soy protein – soy does not have a high bioavailability. Additionally, soy is high in glutamic acid and when freed by hydrolyzing, and used chronically, it can become an excitotoxin/neurotoxin in susceptible people/pets. There may not however be enough freed glutamic acid (and aspartic acids) in the product, at the recommended dose, to be problematic but it is still a concern for me. In my opinion, the hydrolyzed soy is added as a flavor enhancer and flavor enhancers, like MSG, have been scientifically shown to cause various disease states in those susceptible.
I’m not sure if phosphorus builds up in acute kd so by feeding a diet already lower in phosphorus AND using a binder you may not supply enough for the body and create symptoms of low phosphorus. If you’ve had a CBC done and it shows high phosphorus than epikitin may be beneficial.
Epikitin is often recommended with Azodyl (which is a probiotic formulated specifically for kd). I chose to use Primal Defense over Azodyl because PD has a wider variety of beneficial bacteria not just the ones for uremia. On the lower protein diet with the inclusion of Primal Defense I don’t know that Azodyl would benefit Faith but it could be something to look in to? I personally wouldn’t replace PD with it but use it in conjunction with.
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