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I do rescue and have had 3 large breed puppies with SIBO. All 3 have intermittent diarrhea and periodic vomiting. All 3 cleared with no reoccuramce after 6 weeks of Tylan powder aka Tylosin twice a day for 6 weeks and a raw diet. Dosage for the Tylan is:
<10 lbs: 1/16 Tsp BID on food
11-25 lbs: 1/12 Tsp BID on food
26-50 lbs: 1/8 Tsp BID on food
50+ lbs: 1/4 Tsp BID on food
As for the raw diet, Steve’s works well and they will deliver for free (rawpetfood.com)